Boil the bowtie pasta in salted water until al dente, reserving 1/2 cup of the cooking water before draining.
Brown the ground beef in a large skillet with olive oil over medium-high heat, then drain any excess fat.
Sauté the diced onion, minced garlic, Cajun seasoning, and smoked paprika with the beef until fragrant.
Simmer the mixture with beef broth, then melt in the softened cream cheese and heavy cream until smooth.
Toss the drained pasta and Parmesan cheese into the sauce, using pasta water to thin it if needed, and serve hot.